The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

Against the Rams, San Francisco will be without Kittle, running back Christian McCaffrey and receiver Deebo Samuel. McCaffrey ...

The last time the Rams and 49ers met, Sean McVay and Kyle Shanahan were without some starters. This time, star players will be absent yet again.

Since entering the NFL, Brock Purdy has been routinely accused of being a system quarterback. He's often disrespected and overlooked as many believe he is only ...

Jimmy Garoppolo is the Los Angeles Rams' No. 2 quarterback, but that doesn't mean the former 49ers signal-caller isn't ...

Earlier this week, 49ers head coach Kyle Shanahan said he doesn't ask Brock Purdy to do too much on the field. That was an understatement. Shanahan doesn't all ...

NFC West foes San Francisco and Los Angeles face off again on Sunday. Here's what to know about one of the oldest rivalries ...

The 49ers ruled out George Kittle for Sunday’s game at the Rams and elevated tight end Brayden Willis and defensive end Sam ...

The San Francisco 49ers will be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams.

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...

It takes strong resolve from these young quarterbacks to persevere, and it, too, takes the right fit for them to finally make ...