Neuss is a city in North Rhine-Westphalia, Germany. It is located on the west bank of the Rhine opposite Düsseldorf. Neuss is the largest city …Neuss is a city in North Rhine-Westphalia, Germany. It is located on the west bank of the Rhine opposite Düsseldorf. Neuss is the largest city within the Rhein-Kreis Neuss district. It is primarily known for its historic Roman sites, as well as the annual Neusser Bürger-Schützenfest. Neuss and Trier share the title of "Germany's oldest city", and in 1984 Neuss celebrated the 2000th anniversary of its founding in 16 BCE.