Orangeburg, also known as The Burg, is the principal city in and the county seat of Orangeburg County, South Carolina, United States. T…Orangeburg, also known as The Burg, is the principal city in and the county seat of Orangeburg County, South Carolina, United States. The population of the city was 13,964 according to the 2020 census. The city is located 37 miles southeast of Columbia, on the north fork of the Edisto River.
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